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Mounting an HDD could not be easier, take a drive bay bracket (has rubber inserts to prevent resonating noises from the HDD), lock them in and slide the unit into the drive bay until you hear a click. See below.
These brackets can also hold a 2.5" SSD, you'll need to secure it with four mounting screws on the bottom side. It's a very simple solution really, but there's nothing wrong with simple as long as it's functional and effective. You can house a luxurious six 3.5/2.5 drives. And should you need more space, the drive bays are removable as well.
The top HDD caddy can be removed, or repositioned next to the PSU (to the left of the HDD on the photo).
At the bottom side we can see the mounting area for the PSU, underneath it a ventilation mesh, which has dust protection with the help of a filter. Also notice that there is a bracket right here which allows you to install several sizes of PSU. So, should you feel a need to install a longer PSU at one point in time, then that will be possible.