The Sapphire Radeon RX 7900 GRE Pure graphics card features a white and gray color scheme, enhancing its visual appeal. This card is constructed with a plastic cooler shroud and a metal backplate, ensuring durability.The card's cooling efficiency is boosted by angular axial fans, which utilize a dual ball bearing design for extended durability and a double-layer structure to improve airflow by increasing downward pressure. However, the card's length of 320mm might be considered excessive, its 3-slot thickness indicates it is not designed for compact systems. Despite this, the inclusion of a GPU bracket indicates a recognition of the need for additional support due to its size.  The Navi 31 graphics processor boasts a significant die area of 529 mm² and accommodates a colossal 57,700 million transistors. Unlike the Radeon RX 7900 XTX, the GRE variant has strategically disabled certain shading units to achieve the target shader count. Equipped with 5120 shading units, 320 texture mapping units, and 192 Render Output Units (ROPs), along with 80 ray tracing acceleration cores, the Radeon RX 7900 GRE delivers substantial graphics processing power.

The card is equipped with a single lighting zone at the top edge, displaying a red Sapphire logo, which can be turned off with a switch. For connectivity, it includes two DisplayPort 2.1 and two HDMI 2.1a ports, an upgrade from its predecessor's architecture.

AMD has enhanced the card's video processing with two separate hardware units for encoding and decoding videos, or improving a single stream's frame rate. It supports various video codecs for decoding, such as VP9, H.264, H.265, and AV1, and for encoding, H.264, H.265, and AV1.