Grab the new AMD Catalyst Application Profile - 12.9 CAP1 release. These are the Catalyst profiles for multi-GPU support.

This release of ATI Catalyst delivers support for the latest ATI CrossFireX profiles in a separate executable file ensuring users have access to the absolute latest set of profiles installed on their PC.

Latest profiles added :

World of Warcraft - Mist of Pandaria (DX11, DX9): Fixes texture flickering observed when enabling high graphics settings with CrossFire enabled

• World of Warcraft - Mist of Pandaria (DX9): Resolve corruption when enabling Anti-Aliasing through the Catalyst Control Center (Anti-Aliasing should be enabled through the applications settings)
• World of Warcraft - (DX9): Resolves performance issues observed with the 64-bit variant of the client
• Tribes Ascend: Improves CrossFire performanceen running in CrossFire mode
• F1 2012: Improves CrossFire performance, resolves texture flickering in reflections

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• Borderlands 2 – New CrossFire profile
• Guild War 2:  Resolves grass texture corruption observed when changing graphics settings in a CrossFire configuration
• World of Warcraft(DX9):   Fix the flickering observed when view distance is changed to fair in graphics settings when CrossFire is enabled
• Depth Hunter:  Resolves shadow flickering seen when running in CrossFire mode
• Dirt Showdown – Resolves flickering seen in CrossFire mode
• Stalker Call of Pripyat – Resolves flickering seen in CrossFire mode
• War of Roses – Fixes flickering seen in CrossFire mode
• TorchLight 2 – Improves single GPU performance, and disables CrossFire due to incompatible support when running in a Multi-GPU configuration- Hawken: Improves the CrossFire performance

• Diablo 3: Multi Sample Anti-Aliasing and Super Sample Anti-Aliasing can now be enabled for this title through the Catalyst Control Center for single and multi-GPU configurations
• Call of Duty: World at War: Resolve corruption when enabling Anti-Aliasing through the Catalyst Control Center on single GPU configurations
• Call of Duty: Modern Warfare 3 – further improvements to CrossFire performance
• Myths and Heroes 3: Improves CrossFire performance
• XCOM: Enemy Unknown : Improves CrossFire performance
• Tom Clancy Ghost Recon Future Soldier: Improves CrossFire performance and resolves flickering seen when running in CrossFire mode

Older changes:

• Alan Wake American Nightmare : Improves CrossFire performance
• Windows Media Center – Improve performance on APU configurations
• Max Payne 3 (DirectX11 version): Improves single GPU and CrossFire performance
• Diablo 3
  Sudden Attack
  AIO
• Counter Strike: GO: Improves CrossFire performance
• FireFall: Improves CrossFire performance
• Test Drive: Ferrari Legend: Improves CrossFire performance
• Sniper Elite 2: Improves performance for single GPU configurations
• The Walking Dead: Resolve corruption when enabling Anti-Aliasing through the Catalyst Control Center on single GPU configurations
• Blades of Time: Resolve corruption when enabling Anti-Aliasing through the Catalyst Control Center on single GPU configurations
• Majesty HD: Disables CrossFire support, as the title is incompatible with CrossFire
• FireFall: Resolve corruption when enabling Anti-Aliasing through the Catalyst Control Center on single GPU configurations
• Test Drive Unlimited 2: Improves CrossFire performance- Ridge Racer Unbounded: Fixes full screen corruption for single GPU configurations
• Stacking: Resolved image quality issues when enabling Anti-Aliasing through the Catalyst Control Center on single GPU configurations
• Dirt 3: Fixes corruption found in particular scenes when CrossFire is enabled

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• Alan Wake: The American Nightmare - Improves CrossFire performance
• Syndicate – Improves both single GPU and CrossFire performance
• Darkness 2 – Improves CrossFire performance
• Kingdoms of Amalur: Reckoning – Improves CrossFire performance for the AMD Radeon HD 6000 Series to avoid negative scaling at low resolutions
• Natural Selection 2 – Fixes shadow map flickering issue seen with CrossFire enabled

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• Star Wars: The old republic : Improves CrossFire performance and resolves flickering seen on Map
• Unigine Tropics – Resolves flashing shadow reflections with CrossFire enabled
• Wargame: European Escalation: Improves CrossFire performance
• Star Wars: The old republic : Improves CrossFire performance
• Need for Speed: The Run – fixes flashing in terrain, shadows and bushes
• Prototype 2: Improves single GPU and CrossFire performance
• Insane 2: Improves CrossFire performance
• Syndicate - Improves CrossFire performance
• Costume Quest – Resolves image quality issues
• DOTA 2 – Enables CrossFire support for this title
• Project C.A.R.S.(DX9 version) :  Improves CrossFire performance
• Counter Strike: Global Offensive:  Improves CrossFire performance
• Modified Battlefield3 Profile
• Modified Saints Row 3
• ProfileAdded Prototype 2 Profile
• Added Project C.A.R.S Profile
• Added Counter-Strike: Global Offensive Profile
• Added Might and Magic Heroes VI Profile
• Anno 2070: Improves CrossFire scaling and fixes image quality issues seen in water, shadows, etc.
• Call of Duty: Modern Warfare 3: Improves CrossFire performance
• Saints Row 3 (DirectX 9 version): Improves CrossFire performance
• Serious Sam 3: Improves CrossFire performance
• Java Control Panel: Fixes black screen corruption seen on single and multi GPU configurations when Anti-Aliasing is forced on through the Catalyst Control Center
   
• Saints Row 3: Resolves stuttering seen when playing in CrossFireX mode.
• Also provides Single GPU and CrossFireX performance improvements when running in lower resolution configurations
• Gothic 4 Arcania: Fall of Setarrif: Improves CrossFire performance
• Battlefield 3: Tweaks to the CrossFire profile
• Battlefield 3 – Provides great CrossFire scaling and resolves stuttering issues when running in CrossFire mode.
• Deus Ex Missing Link: Improves CrossFire performance
• F1 2011: Improves CrossFire performance
• Dead Island: Improves CrossFire performance
• Batman Arkham City (DX9 version): Improves CrossFire performance
• NBA 2012: Disables CrossFire
• Battlefield 3: Provides great CrossFire scaling and reduces flickering / corruption issues when running in CrossFire mode
• Red Orchestra 2 – Improves CrossFire Performance.
• Serious Sam 3 – Improves CrossFire performance
• Saints Row: The Third – Improves CrossFire performance
• Battlefield 3
• Red Orchestra 2 – Improves CrossFire Performance
• TrackMania propfile added
• Hard Reset – Improves CrossFire performance
• Warhammer 40,000: Space Marine – Improves performance on Single GPU configurations
• War Inc Battle Zone: Resolves image corruption seen when enabling Anti-Aliasing through the Catalyst Control Center
• Call of Juarez The Cartel - Improves CrossFire performance
• Rome Total War: Disables CrossFire support
• F1 2011:
  - Improves performance on Single GPU configurations
  - Forced on Anti-Aliasing through the Catalyst Control Center has been disabled
• Harry Potter and the Deathly Hollows Part 2 - Forced on Anti-Aliasing through the Catalyst Control Center now works
• LA Noire - Improves CrossFire performance
• Need for Speed World – Disable CrossFire support
• Serious Sam HD : The First Encounter – Disable CrossFire support
• Serious Sam HD Demo: The First Encounter – Disable CrossFire support
• Serious Sam HD : The Second Encounter – Disable CrossFire support
• Deus Ex3: Human Revolution(DX9) - Improves CrossFire performance
• Shaun White Skateboarding - Improves CrossFire performance
• MaxPayne3 - Improves CrossFire performance
• Global Ops – Commando Libya: Improves CrossFire performance
• Driver San Francisco: Disables CrossFire

The Secret World (DX11): Resolves corruption seen in HUD/options when running in CrossFire mode

OS: Win7 x32, Win7 x64, WinVista, WinVista x64, WinXP